Aplastic Anemia Essay Example for Free

Aplastic Anemia Essay Aplasitc anemia is a very rare blood disorder. Sometimes, it is connected with leukemia; it could be a result from chemotherapy given to leukemia patients. In aplastic anemia, the bone marrow does not make the necessary blood cells needed in the blood; however, leukemia is when the blood cells are deformed and not working properly. Leukemia is a cancer where as aplastic anemia is not. Chemotherapy treatment for cancer can lead to the secondary condition of aplastic anemia that may cause slowing down of producing blood cells. What are the anatomical and physiological symptoms and causes for aplastic anemia? What is the diagnosis and what treatments are available for aplastic anemia? One symptom is fatigue from being anemic. Anemia is when the red blood cells are low in the blood. The red blood cells carry the oxygen from your lungs to all parts of the body (Aplastic Anemia and MDS International Foundation, Inc. ). This will cause fatigue when the body does not get enough oxygen. There is a little more than just low red blood count in cells in aplastic anemia. It is when the body doesn’t produce all three different blood cells that the body has: white blood cells, red blood cells, and the platelets termed pancytopenia (Wikipedia). In aplastic anemia, it is when the bone marrow stops producing or slows down in producing these new blood cells. The white ones or leukocytes are to fight infections in the body by attacking and killing bacteria and viruses (Aplastic Anemia and MDS International Foundation, Inc. ), so with out them patients easily catch viruses. A low white blood cell count is called neutropenia (Aplastic Anemia and MDS International Foundation, Inc. . The other is the platelets; they are for blood clots. A low platelet count is called thrombocytopenia (Aplastic Anemia and MDS International Foundation, Inc. ). A low platelet count leads to another symptom that would be uncontrolled bleeding because the body does not have the platelets to stop the bleeding. You can also causes bruising and petechiae (Wikipedia). Some of the other symptoms include shortness of breath, headache, pallor and, ultimately tachycardia and heart failure (Lippincott 508). Bone tenderness should not be present (Mc Phee 454). The cause for aplastic anemia develops when the bone marrow is damaged or in some cases is unknown. About 75 out of 100 cases of acquired aplastic anemia are idiopathic (Aplastic Anemia MDS International Foundation, Inc. ). This means they have no known cause. Sometimes, the case can be from radiation and chemotherapy treatment used for cancer. This can destroy the healthy cells in the bone marrow leading to the secondary condition. Some other causes for secondary condition of aplastic anemia are toxic chemicals and certain drugs, such as the chemical benzene that is found in gasoline, or with the use of certain drugs, including chloramphenicol[-0], carbamazepine[-1], felbamate[-2], phenytoin[-3], quinine[-4], and phenylbutazone[-5] (Wikipedia). Chloramphenicol treatment is followed by aplasia in less than 1 in 40,000 treatment courses, and carbamazepine aplasia is even more rare (Wikipedia). The medication for rheumatoid arthritis is connected to ones getting aplastic anemia; this would be called also a secondary condition when aplastic anemia appears. Likewise Lupus, an autoimmune disorder, can attack the healthy stem cells. This would cause the slowing down or stopping of making the blood cells the body needs. The rest may result from immunologic factors (unconfirmed), severe disease (especially hepatitis), viral infection (especially children), or preleukemic and neoplastic infiltration of bone marrow (Lippincott 397). Therefore, to confirm a diagnosis for aplastic anemia they first take a blood sample to see if the blood count is low. If that shows up low in all the blood cells, the next step is to take a bone marrow sample or biopsy. The bone marrow is usually taken from the large hip bone by a needle. The sample is looked at in a microscope to rule out leukemia, which the blood cells would look abnormal and would be the reason the blood cells are not working properly. However, aplastic anemia would show very little red and white blood cells in the blood stream. Some options of treatment given to patients are medications, bone marrow transplant, and blood transfusion (MayoClinic). Just recently, they have stem cell transplants. The medications are immunosuppressive combine with cyclosporine. Maybe one of the causes is the immune system is attacking its own good blood cells, and these drugs will slow down the process. This medication treatment is usually given until the patient can get a stem cell transplant. The other medication can be used with the immunosuppressive is the growth factor. The new genetically engineered growth factor drugs help with making new white blood cells. That is really important, since the body makes a blood cell that only last for awhile, so the body is always generating new blood cells. However, aplastic anemia patients body for some reason stops this process. The other medicines used are antibiotics either to help prevent infections or already established infection, since the immune system is weak and would not be unable to fight of a common cold. Most likely the doctor will administer them before an infection appears, so that the patient will not get an infection. Those are the medications used and if the condition doesn’t improve, the patient would await for a bone marrow transplant. The bone marrow transplant might have been the first choice, which the medication is administered until the patient can find a match donor. The bone marrow transplant is usually a successful treatment to cure aplastic anemia in people under 55 years old (Aplastic Anemia and MDS International Foundation, Inc. ). Bone marrow transplantation from a related, matched donor can treat aplastic anemia – without recurrence- in about four out of five cases (MayoClinic). Up to half the people with matched, but unrelated, donors can expect to have successful bone marrow transplants (MayoClinic). There’s a chance that your body may reject the transplant, leading to life-threatening complications (MayoClinic). The bone marrow transplant uses a matched blood type. When found, the donor will have surgically removed some of his or her healthy bone marrow. It is then injected intravenously in the blood to the patient. The donated bone marrow will collect to the patient’s bone marrow and help with making new blood cells; it may take two to four weeks to show the new blood cells are producing. Before they even give the aplastic patient the donated marrow, they give them chemo to get rid of the diseased marrow, and will also be administered drugs to help prevent rejection of the bone marrow. Another precaution a doctor may limit the number of blood transfusions before the operation to avoid complications. Technology is advancing that they can use stem cells now instead of bone marrow transplant. The new stem cell transplant is taken from the bone marrow, umbilical cord, or the blood stream of the donor. They just get the stem cell from either of those places, and again like the bone marrow transplant, place the stem cell into the blood stream of the patient. The patient will be given chemo before the procedure as in the bone marrow transplant. This time the complication of the new stem cells will create an immune system that attacks the body of the donor, instead of the body rejecting as in the bone marrow transplant. If this does occur, they also have drugs that will help combat this. The treatment of blood transfusion is not usually used because it is a treatment for fatigue. Fatigue is not a medical emergency. First, use rest to see if it alleviates the symptom. White blood cells only last a day because that is how long they last in the body. That is why the bone marrow is important in making the new cells the body needs. The other complication that blood transfusions may cause is hemorrhaging. For long term recovery, they usually need other treatment along with this procedure. Aplastic anemia is a very rare disease and affects very few people. It is not contagious. It is more commonly diagnosed in young adults and children. It can affect any age group anytime in life and the illness might be brief, also it can come on suddenly or slowly. The symptoms vary depending on the blood cells that they are low in. The patient could have a slight case that might just be observed or to a severe case that needs treatment. A doctor should be the one to make the diagnoses and treatments. Doctors estimate that there are about 900 new cases of aplastic anemia diagnosed in the United States each year (Aplastic Anemia MDS International Foundation, Inc. . Patients need to be extra careful not to get an infection because the body having low white blood cell count would have a hard time combating against viruses. Steps are also taken to prevent hemorrhage: avoiding parenteral injections, suggesting the use of an electric razor, humidifying oxygen to prevent dry mucous membranes, and promoting regular bowel movement (Venes 116). Mortality for aplastic anemias with severe pancytopenia is 80% to 90% (Lippincott 507). In advancing technology today, why not consider to be a bone marrow donor that could save lives of others.

Treatment of Change and Expansion in Lotos-Eaters and Rip Van Winkle :: Lotos Winkle

Treatment of Change and Expansion in Lotos-Eaters and Rip Van Winkle      Ã‚   During the Victorian Era, great accomplishments lead to prosperity for the British Empire. Accomplishments include owning nearly a quarter of the world’s land and its people. As a result, trade and commerce expanded, and Great Britain reached the height of its power. Furthermore, science rapidly made progress during this time. These rapid strides in economic and technological advances gave the British people a feeling of pessimism about whether they were progressing for the good. As a result, people began to question man’s place, or duty, on earth. Also occurring within the time of the Victorian Era is the American Renaissance. During this period, Americans were expanding their territory according to the belief in Manifest Destiny, or the idea that God or Nature intended for the United States to spread its civilization from coast to coast. Like the British, Americans questioned their moral responsibility concerning change and expansion. Consequently, the concer ns of the people were echoed in the literature written during these time periods. For example, the Victorian poet, Alfred Tennyson, voiced his concerns about constant change and expansion in "The Lotos-Eaters," while the American writer, Washington Irving, also expressed his concerns in "Rip Van Winkle." An examination of the poem, "The Lotos-Eaters," and the short story, "Rip Van Winkle," reveal that Tennyson and Irving romanticized the concept of stasis while also questioning the duty of change and expansion.    In "The Lotos-Eaters," Tennyson romanticizes nature in order to emphasize the virtues of a land that remains in stasis as opposed to a land that is in constant change. When the mariners land on the island, its is described as a "land where all things always seemà ¢d the same" (Tennyson 24). Tennyson is saying that the beauty of the island has been preserved because no one has attempted to change it. Tennyson is also saying that colonization and expansion lead to industry, which strips nature of its beauty. Furthermore, the atmosphere of the island is romanticized in that "there is neither sharp sunlight nor clear moon, only the haze of a seemingly perpetual afternoon; the air itself is languid and the stream, not full and rushing but slender and slow, seems to pause in its fall from the cliff" (Ryals 97). The idea of an island that remains constantly at the most pleasant time of day and a stream that is barely moving romanticizes the idea of being at rest with no worries.

Marketing assignment Essay

The Goodyear Tire and Rubber Company The Goodyear Tire and Rubber Company is very famous tire producer in North America now, which included race cars tires, truck tires, snow tires, heavy earth-mover tires and automobile tires. It was established in Akron, Ohio, in 1898 by Frank Seiberling, which had only thirteen employees. Moreover, David Hill who is the first president of the company because he purchased the stock of this company. Seiberling borrowed 3,500 dollars from his brother-in-law to purchase the company’s first factory, which is an abandoned factory in Akron. Therefore, Seiberling want to be a good leader to manage this factory. Based on The History of Goodyear Tires (n.d), â€Å"Seiberling then founded the Goodyear Tire and Rubber Company, naming his business venture after Charles Goodyear, who had discovered how to vulcanize rubber to make it harder, more durable and resistant to chemicals† (para.2). The Goodyear Tire and Rubber Company first began to produce bicycle and carriage tires. According to The History of Goodyear Tires (n.d), â€Å"In the first month, Goodyear Tires did a little over $8,000 in business. The company came up with its famous winged-foot logo in the early part of the 20th century† (para.1). Furthermore, Goodyear Company began to produce automobile tires. Then the Goodyear Company build new factory, which is bigger than the first one. Forthemore, they began to led more people know them. Based on The History of Goodyear Company (n.d), â€Å"By 1901, Goodyear had begun to use its now-famous winged-foot logo in advertisements† (para.3). By the 10 years later, the Goodyear Company stared make tires for airplanes, and then as that time Goodyear Company began work for aviation. In 1916, Goodyear Company purchased a plant factory for produce zeppelin aircraft. During the World of War One, Goodyear Company got the order form from the United States  t o built nine zeppelin aircraft. Although, the Goodyear Company was not finish all of the zeppelin aircrafts in the 1917,the expanse for building zeppelin aircraft was hand down and help Goodyear during World of War Two. Otherwise, Goodyear Company also produced airships. According to Goodyear Zeppelin Company, â€Å"Goodyear also manufactured two airships, the Akron and the Macon, for the United States military during the early 1930s. During World War II, the company manufactured 104 airships for the military at its Akron facility† (para.2). Until now, the Goodyear Company still produces the zeppelin aircraft for advertising actions. It is sign for Goodyear Company all-round developing in the world, at this time the Goodyear Company is not only a tire and rubber company, but also become a magnate for rubber manufacture. Therefore, Goodyear Company becomes the third largest tires producer in the world now. In that company, they are very successful for many years that are about the product and place and price. For example, you can see the service in everywhere even in Halifax. That is why Place is very important factor to increase market share and sales quantity. One good place can help us sale more items. During the reach I noticed that people buy the product through the nearly the place. However the product is very famous around the world that is the company force. The good product will catch lots of customer. You can see the tires in the car. They are make lots of advertisement around the all TV shows. That why they sell the product like hot cake. However, they are service is more like the out of mouths. From the advertisement, we can clear know that that the company goal is the sale the tires around the world. For a long historic story from this company the band is the best famous advertisements. People believe in them, that their tires can very successful to sale very thing. Reference The History of Goodyear Tires, Lindell John, http://www.ehow.com/about_4672693_history-goodyear-tires.html Goodyear Zeppelin Company, http://www.ohiohistorycentral.org/entry.php?rec=899

Case Analysis Enron Corporation - 891 Words

PROBLEM (ISSUE) STATEMENT: Having the position that you want, the money you dream about, and the company you love to work for are the things that will absolutely blind your eyes of seeing anything wrong or knowing how this money came from. This is how the employees in Enron Corporation felt at the time when the company was the biggest energy company in the nation, and was having the best stock in the market. â€Å"You could feel the excitement at 6 a.m. You walked in the door and got energized, all those creative juices flowing. You worked with the best, the most brilliant. It was a great, great company, says one of the employees in Enron for New York Times (Turnage and Keyton). Therefore, it is obvious that the employees were having the best time in their lives. In the meantime, it was obvious for them to notice there was something wrong financially, but they ignored it because they were living in paradise. However, Sherron Watkins, Enron vice president, who is known as the whistleblower, knows the problem t hat was happing in Enron, but she was in a dilemma in how to minimize the individual damages by blowing the whistle at the right time. The company got to the point where the employees have moral silence, deafness, and blindness. For moral silence, the employees were avoiding any kind of action against unethical behavior. Deafness is that the employees are not willing to listen to any ethical issues. When talking about moral blindness, the employees do not see the problemShow MoreRelatedThe Fall Of Major Telecommunications Company Onetel And Enron1319 Words   |  6 Pages OneTel and Enron were huge technology companies, dominating the competition that they faced although - everything changed. Both of these companies operated in the same era, coincedently both suffering financial collapse. The reasons were mainly because of failure to follow major accounting principles, lacking morals and lacking strong work ethics. If even a major corporation can fall into this â€Å"trap†, then avoiding doesn’t sound easy, although accountants can easily avoid scandals by following aRead MoreFinancial Collapse : The And Enron1320 Words   |  6 PagesOneTel and Enron were huge technology companies, dominating the competition that they faced although - everything changed. Both of these companies operated in the same era, coincedently both suffering financial collapse. The reasons were mainly because of the failure to follow major accounting principles, lacking morals and lacking strong work ethics. If even a major corporation can fall into this â€Å"t rap†, then avoiding doesn’t sound easy, although accountants can easily avoid scandals by followingRead MoreEnron And The Enron Scandal1588 Words   |  7 PagesEnron was a corporation located in Houston, Texas and in just fifteen years the US energy trading and utilities company grew to become one of America’s largest and more successful cooperation’s. Enron suffered a major fall. After being one of the most successful corporations Enron became the biggest company to file bankruptcy in history. In this research paper it will discuss about the history of Enron, the fraud committed and who is to blame. The historical development of white collar crime in theRead MoreModern White Collar Crime : A Modern Or Postmodern Crime1079 Words   |  5 PagesSociety has made many individuals question Enron scandal in regards to what is a modern or postmodern crime. Modern white collar crime focuses primarily on agriculture, productive activity, hand-tool technology, a nd farming villages as a community or family unit. While, postmodern white collar crime deals with more advanced technology such as computers, virtual communities, television/computer link-ups, and telephone communication. Overall, those who seek a career in criminology must navigate terminologyRead MoreEnron And The Collapse Of Enron1303 Words   |  6 PagesEnron, a company which originated in Huston, Texas, was one of the largest American energy trading corporations in the nation. Although it was one of the most well known companies, it was also one that crashed and burned the fastest, shocking many people when it did. Not only did it end fast, the company caused quite a scandal which is still being discussed and reviewed in today’s world. Enron’s bankruptcy scandal was so widely known because of the many people who associated themselves with the companyRead MoreArthur Andersen: Failure to Report Accurately Essay1214 Words   |  5 PagesEnron Corporation has been accused of cooking the books and overstating company profits in its financial reports. In addition, Enron’s trading business adopted mark-to-market accounting, which meant that once a long-term contract was signed, income was estimated as the present value of net future cash flows, even though in some cases there were serious questions about the viability of these contracts and their associated costs. Author Andersen provided both consulting and auditing services whichRead MoreEnron Scandal1477 Words   |  6 Pagesï » ¿Current issue: Scandals in auditing Enron Scandal 1. Introduction Accounting scandals are political or business scandals which arise with the disclosure of financial misdeeds by trusted executives of corporations or governments. These days, not too often, these scandals are splashed as headlines across media. Why? Because there are complex groups of stakeholders who might be seriously affected by the scandals. Enron scam was the most remarkable scandal in 20 centuries by their institutionalizedRead MoreWhite Collar Crime Fbi Investigation1552 Words   |  7 PagesIntroduction: It was 13 years ago that the announcement of bankruptcy by Enron Corporation, an American energy, commodities and service firm at the time, would unravel a scandal resulting in what is regarded as the most multifaceted white-collar crime FBI investigation conducted in history. High-ranking officials at the Houston-based company swindled investors and managed to further their own wealth through intricate, shifty accounting practices such as listing assets above their true value to increaseRead MoreAnalyzing Ethical Behavior920 Words   |  4 PagesEthics is also particularly imperative when laboring with financial information. It is very hard to have faith in someone managing plenty of money. Corporations in the past have distorted their financial statements in regulation to look superior to stockholders, without thinking of the penalty that may be a consequence if they get caught. If a corporation does not encourage good quality ethical conduct within the business, it is difficult t o confide in the financial statements. Analyzing EthicalRead MoreJaclyn Givens. Kathy Osburn. Management 101. 5/8/17. The1400 Words   |  6 PagesJaclyn Givens Kathy Osburn Management 101 5/8/17 The Enron Era â€Å"Just as character matters in people, it matters in organizations,† says Justin Schultz, a corporate psychologist in Denver. The Enron scandal had a big exposure in 2001 confirming the big secret to the increase in billions. In July 1985, Enron formed the merger of Houston Natural Gas and Omaha-based Inter North. The Enron corporation was an American energy company based in Houston Texas. The corporation’s catastrophe in 2001 signifies